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Cytosine deamination and selection of CpG suppressed clones are the two major independent biological forces that shape codon usage bias in coronaviruses

Using the complete genome sequences of 19 coronavirus genomes, we analyzed the codon usage bias, dinucleotide relative abundance and cytosine deamination in coronavirus genomes. Of the eight codons that contain CpG, six were markedly suppressed. The mean NNU/NNC ratio of the six amino acids using ei...

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Detalles Bibliográficos
Autores principales:	Woo, Patrick C.Y., Wong, Beatrice H.L., Huang, Yi, Lau, Susanna K.P., Yuen, Kwok-Yung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2007
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103290/ https://www.ncbi.nlm.nih.gov/pubmed/17881030 http://dx.doi.org/10.1016/j.virol.2007.08.010

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