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Using drug-excipient interactions for siRNA delivery()
SiRNA is the trigger of RNA interference, a mechanism discovered in the late 1990s. To release the therapeutic potential of this versatile but large and fragile molecule, excipients are used which either interact by electrostatic interaction, passively encapsulate siRNA or are covalently attached to...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Published by Elsevier B.V.
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103333/ https://www.ncbi.nlm.nih.gov/pubmed/21945846 http://dx.doi.org/10.1016/j.addr.2011.09.003 |