Group 2 coronaviruses prevent immediate early interferon induction by protection of viral RNA from host cell recognition

Many viruses encode antagonists to prevent interferon (IFN) induction. Infection of fibroblasts with the murine hepatitis coronavirus (MHV) and SARS-coronavirus (SARS-CoV) did not result in nuclear translocation of interferon-regulatory factor 3 (IRF3), a key transcription factor involved in IFN ind...

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Detalles Bibliográficos
Autores principales: Versteeg, Gijs A., Bredenbeek, Peter J., van den Worm, Sjoerd H.E., Spaan, Willy J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2007
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103335/
https://www.ncbi.nlm.nih.gov/pubmed/17316733
http://dx.doi.org/10.1016/j.virol.2007.01.020

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