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HIV-1 matrix protein repositioning in nucleocapsid region fails to confer virus-like particle assembly
The HIV-1 matrix (MA) protein is similar to nucleocapsid (NC) proteins in its propensity for self-interaction and association with RNA. Here we report on our finding that replacing MA with NC results in the production of wild type (wt)-level RNA and virus-like particles (VLPs). In contrast, construc...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103396/ https://www.ncbi.nlm.nih.gov/pubmed/18550141 http://dx.doi.org/10.1016/j.virol.2008.05.010 |