Conserved amino acids W423 and N424 in receptor-binding domain of SARS-CoV are potential targets for therapeutic monoclonal antibody

The receptor-binding domain (RBD) on spike protein of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is the main region interacting with the viral receptor-ACE2 and is a useful target for induction of neutralizing antibodies against SARS-CoV infection. Here we generated two mono...

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Detalles Bibliográficos
Autores principales: Bian, Chao, Zhang, Xiuqin, Cai, Xingfeng, Zhang, Linqi, Chen, Zhiwei, Zha, Ye, Xu, Ying, Xu, Ke, Lu, Wei, Yan, Linchen, Yuan, Jianwei, Feng, Jiannan, Hao, Pei, Wang, Qidi, Zhao, Guoping, Liu, Gang, Zhu, Xueliang, Shen, Hao, Zheng, Bojian, Shen, Beifen, Sun, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103409/
https://www.ncbi.nlm.nih.gov/pubmed/18986662
http://dx.doi.org/10.1016/j.virol.2008.09.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103409/
https://www.ncbi.nlm.nih.gov/pubmed/18986662
http://dx.doi.org/10.1016/j.virol.2008.09.029

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