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Conserved amino acids W423 and N424 in receptor-binding domain of SARS-CoV are potential targets for therapeutic monoclonal antibody
The receptor-binding domain (RBD) on spike protein of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is the main region interacting with the viral receptor-ACE2 and is a useful target for induction of neutralizing antibodies against SARS-CoV infection. Here we generated two mono...
Autores principales: | Bian, Chao, Zhang, Xiuqin, Cai, Xingfeng, Zhang, Linqi, Chen, Zhiwei, Zha, Ye, Xu, Ying, Xu, Ke, Lu, Wei, Yan, Linchen, Yuan, Jianwei, Feng, Jiannan, Hao, Pei, Wang, Qidi, Zhao, Guoping, Liu, Gang, Zhu, Xueliang, Shen, Hao, Zheng, Bojian, Shen, Beifen, Sun, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103409/ https://www.ncbi.nlm.nih.gov/pubmed/18986662 http://dx.doi.org/10.1016/j.virol.2008.09.029 |
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