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Comparative gonadotoxicity of the chemotherapy drugs cisplatin and carboplatin on prepubertal mouse gonads

The treatment of childhood cancer with chemotherapy drugs can result in infertility in adulthood. Newer generations of drugs are developed to replace parent drugs, with the potential benefits of less toxic side effects. For platinum alkylating-like drugs, in contrast to the parent compound cisplatin...

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Detalles Bibliográficos
Autores principales: Allen, Caroline M, Lopes, Federica, Mitchell, Rod T, Spears, Norah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103569/
https://www.ncbi.nlm.nih.gov/pubmed/31953538
http://dx.doi.org/10.1093/molehr/gaaa008