Cystic renal‐epithelial derived induced pluripotent stem cells from polycystic kidney disease patients

Autosomal‐dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, leading to kidney failure in most patients. In approximately 85% of cases, the disease is caused by mutations in PKD1. How dysregulation of PKD1 leads to cyst formation on a molecular level is unknown....

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Detalles Bibliográficos
Autores principales: Kenter, Annegien T., Rentmeester, Eveline, van Riet, Job, Boers, Ruben, Boers, Joachim, Ghazvini, Mehrnaz, Xavier, Vanessa J., van Leenders, Geert J.L.H., Verhagen, Paul C.M.S., van Til, Marjan E., Eussen, Bert, Losekoot, Monique, de Klein, Annelies, Peters, Dorien J.M., van IJcken, Wilfred F.J., van de Werken, Harmen J.G., Zietse, Robert, Hoorn, Ewout J., Jansen, Gert, Gribnau, Joost H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Pluripotent Stem Cells
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103626/
https://www.ncbi.nlm.nih.gov/pubmed/32163234
http://dx.doi.org/10.1002/sctm.18-0283

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