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NGS Evaluation of Colorectal Cancer Reveals Interferon Gamma Dependent Expression of Immune Checkpoint Genes and Identification of Novel IFNγ Induced Genes

To evaluate the expression of immune checkpoint genes, their concordance with expression of IFNγ, and to identify potential novel ICP related genes (ICPRG) in colorectal cancer (CRC), the biological connectivity of six well documented (“classical”) ICPs (CTLA4, PD1, PDL1, Tim3, IDO1, and LAG3) with...

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Detalles Bibliográficos
Autores principales:	Xu, Lai, Pelosof, Lorraine, Wang, Rong, McFarland, Hugh I., Wu, Wells W., Phue, Je-Nie, Lee, Chun-Ting, Shen, Rong-Fong, Juhl, Hartmut, Wu, Lei-Hong, Alterovitz, Wei-Lun, Petricon, Emanuel, Rosenberg, Amy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103651/ https://www.ncbi.nlm.nih.gov/pubmed/32265897 http://dx.doi.org/10.3389/fimmu.2020.00224

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