Implementation of a three-tiered approach to identify and characterize anti-drug antibodies raised against HIV-specific broadly neutralizing antibodies

The ability to detect, quantify, and interrogate the properties of immune responses raised against biological therapeutics is not only important to our understanding of these molecules, but also to their success in the clinic. A tiered assay approach to identify the presence, specificity, and titer...

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Detalles Bibliográficos
Autores principales: Bharadwaj, Pranay, Riekofski, Cassidy, Lin, Shu, Seaman, Michael S., Garber, David A., Montefiori, David, Sarzotti-Kelsoe, Marcella, Ackerman, Margaret E., Weiner, Joshua A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103756/
https://www.ncbi.nlm.nih.gov/pubmed/32070674
http://dx.doi.org/10.1016/j.jim.2020.112764

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