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Methionyl-tRNA Synthetase Regulates Lifespan in Drosophila

Methionyl-tRNA synthetase (MRS) is essential for translation. MRS mutants reduce global translation, which usually increases lifespan in various genetic models. However, we found that MRS inhibited Drosophila reduced lifespan despite of the reduced protein synthesis. Microarray analysis with MRS inh...

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Detalles Bibliográficos
Autores principales:	Suh, Yoon Seok, Yeom, Eunbyul, Nam, Jong-Woo, Min, Kyung-Jin, Lee, Jeongsoo, Yu, Kweon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7103878/ https://www.ncbi.nlm.nih.gov/pubmed/31940717 http://dx.doi.org/10.14348/molcells.2019.0273

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