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Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs
Linkage-specific DUBs employ different mechanisms to recognize and cleave polyubiquitin chains of specific linkage types. In this issue of Cell Chemical Biology, Flierman et al. (2016) develop a new family of novel non-hydrolyzable diubiquitin probes that will be valuable tools to study how DUBs ach...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104002/ https://www.ncbi.nlm.nih.gov/pubmed/27105279 http://dx.doi.org/10.1016/j.chembiol.2016.04.001 |
| _version_ | 1783512161358708736 |
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| author | Kulathu, Yogesh |
| author_facet | Kulathu, Yogesh |
| author_sort | Kulathu, Yogesh |
| collection | PubMed |
| description | Linkage-specific DUBs employ different mechanisms to recognize and cleave polyubiquitin chains of specific linkage types. In this issue of Cell Chemical Biology, Flierman et al. (2016) develop a new family of novel non-hydrolyzable diubiquitin probes that will be valuable tools to study how DUBs achieve specificity. |
| format | Online Article Text |
| id | pubmed-7104002 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | Elsevier Ltd. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-71040022020-03-31 Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs Kulathu, Yogesh Cell Chem Biol Article Linkage-specific DUBs employ different mechanisms to recognize and cleave polyubiquitin chains of specific linkage types. In this issue of Cell Chemical Biology, Flierman et al. (2016) develop a new family of novel non-hydrolyzable diubiquitin probes that will be valuable tools to study how DUBs achieve specificity. Elsevier Ltd. 2016-04-21 2016-04-21 /pmc/articles/PMC7104002/ /pubmed/27105279 http://dx.doi.org/10.1016/j.chembiol.2016.04.001 Text en © 2016 Elsevier Ltd. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Article Kulathu, Yogesh Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs |
| title | Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs |
| title_full | Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs |
| title_fullStr | Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs |
| title_full_unstemmed | Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs |
| title_short | Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs |
| title_sort | novel diubiquitin probes expand the chemical toolkit to study dubs |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104002/ https://www.ncbi.nlm.nih.gov/pubmed/27105279 http://dx.doi.org/10.1016/j.chembiol.2016.04.001 |
| work_keys_str_mv | AT kulathuyogesh noveldiubiquitinprobesexpandthechemicaltoolkittostudydubs |