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Novel Diubiquitin Probes Expand the Chemical Toolkit to Study DUBs
Linkage-specific DUBs employ different mechanisms to recognize and cleave polyubiquitin chains of specific linkage types. In this issue of Cell Chemical Biology, Flierman et al. (2016) develop a new family of novel non-hydrolyzable diubiquitin probes that will be valuable tools to study how DUBs ach...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier Ltd.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104002/ https://www.ncbi.nlm.nih.gov/pubmed/27105279 http://dx.doi.org/10.1016/j.chembiol.2016.04.001 |