Virus infection-induced host mRNA degradation and potential application of live cell imaging

Viruses exist wherever there is life. They can cause allergy, immune response, inflammation, and even fatal diseases directly or indirectly. Accumulating evidence shows that host RNA undergoes rapid degradation during virus infection. Herein, we focus on several possible mechanisms of infection-indu...

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Detalles Bibliográficos
Autores principales: Qi, Dan, Guan, Jitian, Wu, Erxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beijing You'an Hospital affiliated to Capital Medical University. Production and hosting by Elsevier B.V. 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104030/
https://www.ncbi.nlm.nih.gov/pubmed/32289070
http://dx.doi.org/10.1016/j.jrid.2018.12.002
Descripción
Sumario:Viruses exist wherever there is life. They can cause allergy, immune response, inflammation, and even fatal diseases directly or indirectly. Accumulating evidence shows that host RNA undergoes rapid degradation during virus infection. Herein, we focus on several possible mechanisms of infection-induced host RNA turnover, which seems to be a common strategy for both prokaryotic and eukaryotic viruses during the very early stage of infection and a potential application of live cell imaging on its visualization.

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