Virus infection-induced host mRNA degradation and potential application of live cell imaging

Viruses exist wherever there is life. They can cause allergy, immune response, inflammation, and even fatal diseases directly or indirectly. Accumulating evidence shows that host RNA undergoes rapid degradation during virus infection. Herein, we focus on several possible mechanisms of infection-indu...

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Detalles Bibliográficos
Autores principales: Qi, Dan, Guan, Jitian, Wu, Erxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beijing You'an Hospital affiliated to Capital Medical University. Production and hosting by Elsevier B.V. 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104030/
https://www.ncbi.nlm.nih.gov/pubmed/32289070
http://dx.doi.org/10.1016/j.jrid.2018.12.002
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author Qi, Dan
Guan, Jitian
Wu, Erxi
author_facet Qi, Dan
Guan, Jitian
Wu, Erxi
author_sort Qi, Dan
collection PubMed
description Viruses exist wherever there is life. They can cause allergy, immune response, inflammation, and even fatal diseases directly or indirectly. Accumulating evidence shows that host RNA undergoes rapid degradation during virus infection. Herein, we focus on several possible mechanisms of infection-induced host RNA turnover, which seems to be a common strategy for both prokaryotic and eukaryotic viruses during the very early stage of infection and a potential application of live cell imaging on its visualization.
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spelling pubmed-71040302020-03-31 Virus infection-induced host mRNA degradation and potential application of live cell imaging Qi, Dan Guan, Jitian Wu, Erxi Radiol Infect Dis Review Viruses exist wherever there is life. They can cause allergy, immune response, inflammation, and even fatal diseases directly or indirectly. Accumulating evidence shows that host RNA undergoes rapid degradation during virus infection. Herein, we focus on several possible mechanisms of infection-induced host RNA turnover, which seems to be a common strategy for both prokaryotic and eukaryotic viruses during the very early stage of infection and a potential application of live cell imaging on its visualization. Beijing You'an Hospital affiliated to Capital Medical University. Production and hosting by Elsevier B.V. 2018-12 2018-12-12 /pmc/articles/PMC7104030/ /pubmed/32289070 http://dx.doi.org/10.1016/j.jrid.2018.12.002 Text en © 2018 Beijing You'an Hospital affiliated to Capital Medical University. Production and hosting by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Qi, Dan
Guan, Jitian
Wu, Erxi
Virus infection-induced host mRNA degradation and potential application of live cell imaging
title Virus infection-induced host mRNA degradation and potential application of live cell imaging
title_full Virus infection-induced host mRNA degradation and potential application of live cell imaging
title_fullStr Virus infection-induced host mRNA degradation and potential application of live cell imaging
title_full_unstemmed Virus infection-induced host mRNA degradation and potential application of live cell imaging
title_short Virus infection-induced host mRNA degradation and potential application of live cell imaging
title_sort virus infection-induced host mrna degradation and potential application of live cell imaging
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104030/
https://www.ncbi.nlm.nih.gov/pubmed/32289070
http://dx.doi.org/10.1016/j.jrid.2018.12.002
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