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d-chiro-Inositol Ribophostin: A Highly Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities

[Image: see text] Analogues of the Ca(2+)-releasing intracellular messenger d-myo-inositol 1,4,5-trisphosphate [1, Ins(1,4,5)P(3)] are important synthetic targets. Replacement of the α-glucopyranosyl motif in the natural product mimic adenophostin 2 by d-chiro-inositol in d-chiro-inositol adenophost...

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Detalles Bibliográficos
Autores principales:	Mills, Stephen J., Rossi, Ana M., Konieczny, Vera, Bakowski, Daniel, Taylor, Colin W., Potter, Barry V. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104261/ https://www.ncbi.nlm.nih.gov/pubmed/32052631 http://dx.doi.org/10.1021/acs.jmedchem.9b01986

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