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Splice variant of growth hormone-releasing hormone receptor drives esophageal squamous cell carcinoma conferring a therapeutic target

The extrahypothalamic growth hormone-releasing hormone (GHRH) and its cognate receptors (GHRH-Rs) and splice variants are expressed in a variety of cancers. It has been shown that the pituitary type of GHRH-R (pGHRH-R) mediates the inhibition of tumor growth induced by GHRH-R antagonists. However, G...

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Detalles Bibliográficos
Autores principales: Xiong, Xiao, Ke, Xiurong, Wang, Lu, Yao, Zhimeng, Guo, Yi, Zhang, Xianyang, Chen, Yuping, Pang, Chi Pui, Schally, Andrew V., Zhang, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104313/
https://www.ncbi.nlm.nih.gov/pubmed/32156725
http://dx.doi.org/10.1073/pnas.1913433117

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