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IL-4 Alleviates Ischaemia-Reperfusion Injury by Inducing Kupffer Cells M2 Polarization via STAT6-JMJD3 Pathway after Rat Liver Transplantation

BACKGROUND: Liver ischaemia-reperfusion injury (IRI) remains a problem in liver transplantation. Interleukin-4 (IL-4) has been found to reduce liver IRI, but the exact mechanism remains unclear. METHODS: Donor livers were infused with recombinant IL-4 or normal saline during cold storage, and the he...

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Detalles Bibliográficos
Autores principales:	Deng, Minghua, Wang, Jingyuan, Wu, Hao, Wang, Menghao, Cao, Ding, Li, Jinzheng, Wu, Yakun, Gong, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104314/ https://www.ncbi.nlm.nih.gov/pubmed/32258110 http://dx.doi.org/10.1155/2020/2953068

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