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The role of APOE4 in Alzheimer’s disease: strategies for future therapeutic interventions

Alzheimer’s disease (AD) is the leading cause of dementia affecting almost 50 million people worldwide. The ε4 allele of Apolipoprotein E (APOE) is the strongest known genetic risk factor for late-onset AD cases, with homozygous APOE4 carriers being approximately 15-times more likely to develop the...

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Detalles Bibliográficos
Autores principales:	Hunsberger, Holly C., Pinky, Priyanka D., Smith, Warren, Suppiramaniam, Vishnu, Reed, Miranda N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Aging
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104324/ https://www.ncbi.nlm.nih.gov/pubmed/32269835 http://dx.doi.org/10.1042/NS20180203

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