Targeting PML in triple negative breast cancer elicits growth suppression and senescence

Oncogene addiction postulates that the survival and growth of certain tumor cells is dependent upon the activity of one oncogene, despite their multiple genetic and epigenetic abnormalities. This phenomenon provides a foundation for molecular targeted therapy and a rationale for oncogene-based strat...

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Detalles Bibliográficos
Autores principales: Arreal, Leire, Piva, Marco, Fernández, Sonia, Revandkar, Ajinkya, Schaub- Clerigué, Ariane, Villanueva, Josep, Zabala-Letona, Amaia, Pujana, Mikel, Astobiza, Ianire, Cortazar, Ana Rosa, Hermanova, Ivana, Bozal-Basterra, Laura, Arruabarrena-Aristorena, Amaia, Crespo, Jana R., Valcarcel-Jimenez, Lorea, Zúñiga-García, Patricia, Canals, Francesc, Torrano, Veronica, Barrio, Rosa, Sutherland, James D., Alimonti, Andrea, Martin-Martin, Natalia, Carracedo, Arkaitz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104349/
https://www.ncbi.nlm.nih.gov/pubmed/31570853
http://dx.doi.org/10.1038/s41418-019-0407-5

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