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The DNA secondary structures at telomeres and genome instability

Telomeric DNA are TTAGGG tandem repeats, which are susceptible for oxidative DNA damage and hotspot regions for formation of DNA secondary structures such as t-loop, D-loop, G-quadruplexes (G4), and R-loop. In the past two decades, unique DNA or RNA secondary structures at telomeres or some specific...

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Detalles Bibliográficos
Autores principales: Tan, Jun, Lan, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104500/
https://www.ncbi.nlm.nih.gov/pubmed/32257105
http://dx.doi.org/10.1186/s13578-020-00409-z