Dying tumor cell-derived exosomal miR-194-5p potentiates survival and repopulation of tumor repopulating cells upon radiotherapy in pancreatic cancer

BACKGROUND: Tumor repopulation is a major cause of radiotherapy failure. Previous investigations highlighted that dying tumor cells played vital roles in tumor repopulation through promoting proliferation of the residual tumor repopulating cells (TRCs). However, TRCs also suffer DNA damage after rad...

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Detalles Bibliográficos
Autores principales: Jiang, Ming-jie, Chen, Yi-yun, Dai, Juan-juan, Gu, Dian-na, Mei, Zhu, Liu, Fu-rao, Huang, Qian, Tian, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104536/
https://www.ncbi.nlm.nih.gov/pubmed/32228703
http://dx.doi.org/10.1186/s12943-020-01178-6

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