Methods for the reliable induction of heterotopic ossification in the conditional Alk2(Q207D) mouse

OBJECTIVE: Conditional ALK2(Q207D-floxed) (caALK2(fl)) mice have previously been used as a model of heterotopic ossification (HO). However, HO formation in this model can be highly variable, and it is unclear which methods reliably induce HO. Hence, these studies report validated methods for reprodu...

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Detalles Bibliográficos
Autores principales: Pan, Haichun, Fleming, Nicole, Hong, Charles C, Mishina, Yuji, Perrien, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society of Musculoskeletal and Neuronal Interactions 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104591/
https://www.ncbi.nlm.nih.gov/pubmed/32131380

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