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Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in Wuhan, China has posed a serious threat to global public health. To develop specific anti-coronavirus therapeutics and prophylactics, the molecular mechanism that underlies viral infection must first be defined....

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Detalles Bibliográficos
Autores principales: Xia, Shuai, Liu, Meiqin, Wang, Chao, Xu, Wei, Lan, Qiaoshuai, Feng, Siliang, Qi, Feifei, Bao, Linlin, Du, Lanying, Liu, Shuwen, Qin, Chuan, Sun, Fei, Shi, Zhengli, Zhu, Yun, Jiang, Shibo, Lu, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104723/
https://www.ncbi.nlm.nih.gov/pubmed/32231345
http://dx.doi.org/10.1038/s41422-020-0305-x