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Inhibition of SARS-CoV-2 (previously 2019-nCoV) infection by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion
The recent outbreak of coronavirus disease (COVID-19) caused by SARS-CoV-2 infection in Wuhan, China has posed a serious threat to global public health. To develop specific anti-coronavirus therapeutics and prophylactics, the molecular mechanism that underlies viral infection must first be defined....
Autores principales: | Xia, Shuai, Liu, Meiqin, Wang, Chao, Xu, Wei, Lan, Qiaoshuai, Feng, Siliang, Qi, Feifei, Bao, Linlin, Du, Lanying, Liu, Shuwen, Qin, Chuan, Sun, Fei, Shi, Zhengli, Zhu, Yun, Jiang, Shibo, Lu, Lu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104723/ https://www.ncbi.nlm.nih.gov/pubmed/32231345 http://dx.doi.org/10.1038/s41422-020-0305-x |
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