Turning Up Your Nose for a Flaviviral Encephalitis Cure

siRNA approaches have demonstrated promise in treating viral infections in animal models, but poor delivery limits clinical application. In this issue of Cell Host & Microbe, Beloor et al. (2018) report that nose-to-brain delivery of viral-targeted siRNA cures mice from West Nile virus encephali...

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Detalles Bibliográficos
Autores principales: Barouch-Bentov, Rina, Einav, Shirit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
In Translation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104965/
https://www.ncbi.nlm.nih.gov/pubmed/29649437
http://dx.doi.org/10.1016/j.chom.2018.03.014
Descripción
Sumario:siRNA approaches have demonstrated promise in treating viral infections in animal models, but poor delivery limits clinical application. In this issue of Cell Host & Microbe, Beloor et al. (2018) report that nose-to-brain delivery of viral-targeted siRNA cures mice from West Nile virus encephalitis, with potential implications for human infection.

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