Turning Up Your Nose for a Flaviviral Encephalitis Cure

siRNA approaches have demonstrated promise in treating viral infections in animal models, but poor delivery limits clinical application. In this issue of Cell Host & Microbe, Beloor et al. (2018) report that nose-to-brain delivery of viral-targeted siRNA cures mice from West Nile virus encephali...

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Detalles Bibliográficos
Autores principales: Barouch-Bentov, Rina, Einav, Shirit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
In Translation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104965/
https://www.ncbi.nlm.nih.gov/pubmed/29649437
http://dx.doi.org/10.1016/j.chom.2018.03.014
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author Barouch-Bentov, Rina
Einav, Shirit
author_facet Barouch-Bentov, Rina
Einav, Shirit
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description siRNA approaches have demonstrated promise in treating viral infections in animal models, but poor delivery limits clinical application. In this issue of Cell Host & Microbe, Beloor et al. (2018) report that nose-to-brain delivery of viral-targeted siRNA cures mice from West Nile virus encephalitis, with potential implications for human infection.
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spelling pubmed-71049652020-03-31 Turning Up Your Nose for a Flaviviral Encephalitis Cure Barouch-Bentov, Rina Einav, Shirit Cell Host Microbe In Translation siRNA approaches have demonstrated promise in treating viral infections in animal models, but poor delivery limits clinical application. In this issue of Cell Host & Microbe, Beloor et al. (2018) report that nose-to-brain delivery of viral-targeted siRNA cures mice from West Nile virus encephalitis, with potential implications for human infection. Elsevier Inc. 2018-04-11 2018-04-11 /pmc/articles/PMC7104965/ /pubmed/29649437 http://dx.doi.org/10.1016/j.chom.2018.03.014 Text en © 2018 Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle In Translation
Barouch-Bentov, Rina
Einav, Shirit
Turning Up Your Nose for a Flaviviral Encephalitis Cure
title Turning Up Your Nose for a Flaviviral Encephalitis Cure
title_full Turning Up Your Nose for a Flaviviral Encephalitis Cure
title_fullStr Turning Up Your Nose for a Flaviviral Encephalitis Cure
title_full_unstemmed Turning Up Your Nose for a Flaviviral Encephalitis Cure
title_short Turning Up Your Nose for a Flaviviral Encephalitis Cure
title_sort turning up your nose for a flaviviral encephalitis cure
topic In Translation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104965/
https://www.ncbi.nlm.nih.gov/pubmed/29649437
http://dx.doi.org/10.1016/j.chom.2018.03.014
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