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The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
The problem of the asymptotic dynamics of a quarantine/isolation model with time delay is considered, subject to two incidence functions, namely standard incidence and the Holling type II (saturated) incidence function. Rigorous qualitative analysis of the model shows that it exhibits essentially th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105019/ https://www.ncbi.nlm.nih.gov/pubmed/32288639 http://dx.doi.org/10.1016/j.nonrwa.2010.06.009 |
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author | Safi, Mohammad A. Gumel, Abba B. |
author_facet | Safi, Mohammad A. Gumel, Abba B. |
author_sort | Safi, Mohammad A. |
collection | PubMed |
description | The problem of the asymptotic dynamics of a quarantine/isolation model with time delay is considered, subject to two incidence functions, namely standard incidence and the Holling type II (saturated) incidence function. Rigorous qualitative analysis of the model shows that it exhibits essentially the same (equilibrium) dynamics regardless of which of the two incidence functions is used. In particular, for each of the two incidence functions, the model has a globally asymptotically stable disease-free equilibrium whenever the associated reproduction threshold quantity is less than unity. Further, it has a unique endemic equilibrium when the threshold quantity exceeds unity. For the case with the Holling type II incidence function, it is shown that the unique endemic equilibrium of the model is globally asymptotically stable for a special case. The permanence of the disease is also established for the model with the Holling type II incidence function. Furthermore, it is shown that adding time delay to and/or replacing the standard incidence function with the Holling type II incidence function in the corresponding autonomous quarantine/isolation model with standard incidence (considered in Safi and Gumel (2010) [10]) does not alter the qualitative dynamics of the autonomous system (with respect to the elimination or persistence of the disease). Finally, numerical simulations of the model with standard incidence show that the disease burden decreases with increasing time delay (incubation period). Furthermore, models with time delay seem to be more suitable for modeling the 2003 SARS outbreaks than those without time delay. |
format | Online Article Text |
id | pubmed-7105019 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71050192020-03-31 The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay Safi, Mohammad A. Gumel, Abba B. Nonlinear Anal Real World Appl Article The problem of the asymptotic dynamics of a quarantine/isolation model with time delay is considered, subject to two incidence functions, namely standard incidence and the Holling type II (saturated) incidence function. Rigorous qualitative analysis of the model shows that it exhibits essentially the same (equilibrium) dynamics regardless of which of the two incidence functions is used. In particular, for each of the two incidence functions, the model has a globally asymptotically stable disease-free equilibrium whenever the associated reproduction threshold quantity is less than unity. Further, it has a unique endemic equilibrium when the threshold quantity exceeds unity. For the case with the Holling type II incidence function, it is shown that the unique endemic equilibrium of the model is globally asymptotically stable for a special case. The permanence of the disease is also established for the model with the Holling type II incidence function. Furthermore, it is shown that adding time delay to and/or replacing the standard incidence function with the Holling type II incidence function in the corresponding autonomous quarantine/isolation model with standard incidence (considered in Safi and Gumel (2010) [10]) does not alter the qualitative dynamics of the autonomous system (with respect to the elimination or persistence of the disease). Finally, numerical simulations of the model with standard incidence show that the disease burden decreases with increasing time delay (incubation period). Furthermore, models with time delay seem to be more suitable for modeling the 2003 SARS outbreaks than those without time delay. Elsevier Ltd. 2011-02 2010-06-30 /pmc/articles/PMC7105019/ /pubmed/32288639 http://dx.doi.org/10.1016/j.nonrwa.2010.06.009 Text en Copyright © 2010 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Safi, Mohammad A. Gumel, Abba B. The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay |
title | The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay |
title_full | The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay |
title_fullStr | The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay |
title_full_unstemmed | The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay |
title_short | The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay |
title_sort | effect of incidence functions on the dynamics of a quarantine/isolation model with time delay |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105019/ https://www.ncbi.nlm.nih.gov/pubmed/32288639 http://dx.doi.org/10.1016/j.nonrwa.2010.06.009 |
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