Cargando…

The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay

The problem of the asymptotic dynamics of a quarantine/isolation model with time delay is considered, subject to two incidence functions, namely standard incidence and the Holling type II (saturated) incidence function. Rigorous qualitative analysis of the model shows that it exhibits essentially th...

Descripción completa

Detalles Bibliográficos
Autores principales: Safi, Mohammad A., Gumel, Abba B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105019/
https://www.ncbi.nlm.nih.gov/pubmed/32288639
http://dx.doi.org/10.1016/j.nonrwa.2010.06.009
_version_ 1783512325146279936
author Safi, Mohammad A.
Gumel, Abba B.
author_facet Safi, Mohammad A.
Gumel, Abba B.
author_sort Safi, Mohammad A.
collection PubMed
description The problem of the asymptotic dynamics of a quarantine/isolation model with time delay is considered, subject to two incidence functions, namely standard incidence and the Holling type II (saturated) incidence function. Rigorous qualitative analysis of the model shows that it exhibits essentially the same (equilibrium) dynamics regardless of which of the two incidence functions is used. In particular, for each of the two incidence functions, the model has a globally asymptotically stable disease-free equilibrium whenever the associated reproduction threshold quantity is less than unity. Further, it has a unique endemic equilibrium when the threshold quantity exceeds unity. For the case with the Holling type II incidence function, it is shown that the unique endemic equilibrium of the model is globally asymptotically stable for a special case. The permanence of the disease is also established for the model with the Holling type II incidence function. Furthermore, it is shown that adding time delay to and/or replacing the standard incidence function with the Holling type II incidence function in the corresponding autonomous quarantine/isolation model with standard incidence (considered in Safi and Gumel (2010) [10]) does not alter the qualitative dynamics of the autonomous system (with respect to the elimination or persistence of the disease). Finally, numerical simulations of the model with standard incidence show that the disease burden decreases with increasing time delay (incubation period). Furthermore, models with time delay seem to be more suitable for modeling the 2003 SARS outbreaks than those without time delay.
format Online
Article
Text
id pubmed-7105019
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Elsevier Ltd.
record_format MEDLINE/PubMed
spelling pubmed-71050192020-03-31 The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay Safi, Mohammad A. Gumel, Abba B. Nonlinear Anal Real World Appl Article The problem of the asymptotic dynamics of a quarantine/isolation model with time delay is considered, subject to two incidence functions, namely standard incidence and the Holling type II (saturated) incidence function. Rigorous qualitative analysis of the model shows that it exhibits essentially the same (equilibrium) dynamics regardless of which of the two incidence functions is used. In particular, for each of the two incidence functions, the model has a globally asymptotically stable disease-free equilibrium whenever the associated reproduction threshold quantity is less than unity. Further, it has a unique endemic equilibrium when the threshold quantity exceeds unity. For the case with the Holling type II incidence function, it is shown that the unique endemic equilibrium of the model is globally asymptotically stable for a special case. The permanence of the disease is also established for the model with the Holling type II incidence function. Furthermore, it is shown that adding time delay to and/or replacing the standard incidence function with the Holling type II incidence function in the corresponding autonomous quarantine/isolation model with standard incidence (considered in Safi and Gumel (2010) [10]) does not alter the qualitative dynamics of the autonomous system (with respect to the elimination or persistence of the disease). Finally, numerical simulations of the model with standard incidence show that the disease burden decreases with increasing time delay (incubation period). Furthermore, models with time delay seem to be more suitable for modeling the 2003 SARS outbreaks than those without time delay. Elsevier Ltd. 2011-02 2010-06-30 /pmc/articles/PMC7105019/ /pubmed/32288639 http://dx.doi.org/10.1016/j.nonrwa.2010.06.009 Text en Copyright © 2010 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Safi, Mohammad A.
Gumel, Abba B.
The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
title The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
title_full The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
title_fullStr The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
title_full_unstemmed The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
title_short The effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
title_sort effect of incidence functions on the dynamics of a quarantine/isolation model with time delay
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105019/
https://www.ncbi.nlm.nih.gov/pubmed/32288639
http://dx.doi.org/10.1016/j.nonrwa.2010.06.009
work_keys_str_mv AT safimohammada theeffectofincidencefunctionsonthedynamicsofaquarantineisolationmodelwithtimedelay
AT gumelabbab theeffectofincidencefunctionsonthedynamicsofaquarantineisolationmodelwithtimedelay
AT safimohammada effectofincidencefunctionsonthedynamicsofaquarantineisolationmodelwithtimedelay
AT gumelabbab effectofincidencefunctionsonthedynamicsofaquarantineisolationmodelwithtimedelay