Phage display technique identifies the interaction of severe acute respiratory syndrome coronavirus open reading frame 6 protein with nuclear pore complex interacting protein NPIPB3 in modulating Type I interferon antagonism

BACKGROUND/PURPOSE: Severe acute respiratory syndrome coronavirus (SARS-CoV) proteins including ORF6 inhibit Type I interferon (IFN) signaling. METHODS: This study identified SARS-CoV ORF6-interacting proteins using the phage displayed human lung cDNA libraries, and examined the association of ORF6–...

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Detalles Bibliográficos
Autores principales: Huang, Su-Hua, Lee, Tzu-Ying, Lin, Ying-Ju, Wan, Lei, Lai, Chih-Ho, Lin, Cheng-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105049/
https://www.ncbi.nlm.nih.gov/pubmed/26320399
http://dx.doi.org/10.1016/j.jmii.2015.07.002

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