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Investigation of the molecular biology underlying the pronounced high gene targeting frequency at the Myh9 gene locus in mouse embryonic stem cells

The generation of genetically modified mouse models derived from gene targeting (GT) in mouse embryonic stem (ES) cells (mESCs) has greatly advanced both basic and clinical research. Our previous finding that gene targeting at the Myh9 exon2 site in mESCs has a pronounced high homologous recombinati...

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Detalles Bibliográficos
Autores principales:	Tan, Lei, Hu, Yi, Li, Yalan, Yang, Lingchen, Cai, Xiong, Liu, Wei, He, Jiayi, Wu, Yingxin, Liu, Tanbin, Wang, Naidong, Yang, Yi, Adelstein, Robert S., Wang, Aibing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105122/ https://www.ncbi.nlm.nih.gov/pubmed/32226034 http://dx.doi.org/10.1371/journal.pone.0230126

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