Cracking the riddle of dedifferentiated liposarcoma: is EV-MDM2 a key?

Dedifferentiated liposarcoma (DDLPS) is molecularly characterized by wt p53 and MDM2 gene amplification causing MDM2 protein over-production, the key oncogenic process in DDLPS. Commonly located in fat-bearing retroperitoneal areas, almost 60% of DDLPS patients undergo multifocal recurrence, typical...

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Detalles Bibliográficos
Autores principales: Casadei, Lucia, Pollock, Raphael E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105156/
https://www.ncbi.nlm.nih.gov/pubmed/32258243
http://dx.doi.org/10.18632/oncoscience.497

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