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A genome-wide CRISPR/Cas9 screen reveals that the aryl hydrocarbon receptor stimulates sphingolipid levels

Sphingolipid biosynthesis generates lipids for membranes and signaling that are crucial for many developmental and physiological processes. In some cases, large amounts of specific sphingolipids must be synthesized for specialized physiological functions, such as during axon myelination. How sphingo...

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Detalles Bibliográficos
Autores principales:	Majumder, Saurav, Kono, Mari, Lee, Y. Terry, Byrnes, Colleen, Li, Cuiling, Tuymetova, Galina, Proia, Richard L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Accelerated Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105297/ https://www.ncbi.nlm.nih.gov/pubmed/32029474 http://dx.doi.org/10.1074/jbc.AC119.011170

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