Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin

Most cutaneous adverse drug reactions reported in association with chemotherapy, such as a limited maculopapular rash, are considered mild and do not affect the continuation of the treatment. Toxic epidermal necrolysis (TEN), however, is a life-threatening reaction that needs treatment discontinuati...

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Detalles Bibliográficos
Autor principal: Eichhoff, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cancer Intelligence 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105330/
https://www.ncbi.nlm.nih.gov/pubmed/32256693
http://dx.doi.org/10.3332/ecancer.2020.1010
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author Eichhoff, Gerhard
author_facet Eichhoff, Gerhard
author_sort Eichhoff, Gerhard
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description Most cutaneous adverse drug reactions reported in association with chemotherapy, such as a limited maculopapular rash, are considered mild and do not affect the continuation of the treatment. Toxic epidermal necrolysis (TEN), however, is a life-threatening reaction that needs treatment discontinuation. The present case shows the slow progression from a pemetrexed and carboplatin-associated maculopapular rash to a TEN-like reaction.
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spelling pubmed-71053302020-04-01 Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin Eichhoff, Gerhard Ecancermedicalscience Case Report Most cutaneous adverse drug reactions reported in association with chemotherapy, such as a limited maculopapular rash, are considered mild and do not affect the continuation of the treatment. Toxic epidermal necrolysis (TEN), however, is a life-threatening reaction that needs treatment discontinuation. The present case shows the slow progression from a pemetrexed and carboplatin-associated maculopapular rash to a TEN-like reaction. Cancer Intelligence 2020-02-13 /pmc/articles/PMC7105330/ /pubmed/32256693 http://dx.doi.org/10.3332/ecancer.2020.1010 Text en © the authors; licensee ecancermedicalscience. http://creativecommons.org/licenses/by/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Eichhoff, Gerhard
Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin
title Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin
title_full Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin
title_fullStr Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin
title_full_unstemmed Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin
title_short Slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin
title_sort slowly developing toxic epidermal necrolysis-like reaction associated with pemetrexed and carboplatin
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105330/
https://www.ncbi.nlm.nih.gov/pubmed/32256693
http://dx.doi.org/10.3332/ecancer.2020.1010
work_keys_str_mv AT eichhoffgerhard slowlydevelopingtoxicepidermalnecrolysislikereactionassociatedwithpemetrexedandcarboplatin

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