Extracellular matrix-inducing Sox9 promotes both basal progenitor proliferation and gliogenesis in developing neocortex

Neocortex expansion is largely based on the proliferative capacity of basal progenitors (BPs), which is increased by extracellular matrix (ECM) components via integrin signaling. Here we show that the transcription factor Sox9 drives expression of ECM components and that laminin 211 increases BP pro...

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Detalles Bibliográficos
Autores principales: Güven, Ayse, Kalebic, Nereo, Long, Katherine R, Florio, Marta, Vaid, Samir, Brandl, Holger, Stenzel, Denise, Huttner, Wieland B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105383/
https://www.ncbi.nlm.nih.gov/pubmed/32191207
http://dx.doi.org/10.7554/eLife.49808

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