Cargando…
Transcriptome Profile of Nicotinic Receptor-Linked Sensitization of Beta Amyloid Neurotoxicity
Understanding the specific gene changes underlying the prodromic stages of Alzheimer’s disease pathogenesis will aid the development of new, targeted therapeutic strategies for this neurodegenerative disorder. Here, we employed RNA-sequencing to analyze global differential gene expression in a defin...
Autores principales: | Arora, Komal, Belcaid, Mahdi, Lantz, Megan J., Taketa, Ruth, Nichols, Robert A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105468/ https://www.ncbi.nlm.nih.gov/pubmed/32231242 http://dx.doi.org/10.1038/s41598-020-62726-0 |
Ejemplares similares
-
The Neuroprotective Beta Amyloid Hexapeptide Core Reverses Deficits in Synaptic Plasticity in the 5xFAD APP/PS1 Mouse Model
por: Forest, Kelly H., et al.
Publicado: (2021) -
Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity
por: Barykin, Evgeny P., et al.
Publicado: (2019) -
Halogenation Generates Effective Modulators of Amyloid-Beta Aggregation and Neurotoxicity
por: Wong, H. Edward, et al.
Publicado: (2013) -
Affected albumin endocytosis as a new neurotoxicity mechanism of amyloid beta
por: Rasgado, Lourdes A. Vega, et al.
Publicado: (2020) -
Neurotoxicity of different amyloid beta subspecies in mice and their interaction with isoflurane anaesthesia
por: Borgstedt, Laura, et al.
Publicado: (2020)