Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging

Precursor B-cell lymphoblastic lymphoma (PBLL) is a rare subtype of non-Hodgkin lymphoma originating from B-cell precursors. PBLL, as a solitary mass lesion affecting the central nervous system without leukemic disease at presentation, is quite uncommon. Here we report a rare PBLL case with Philadel...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Xiang, Zhou, Weiyan, Xu, Mengqiao, Hua, Tao, Guan, Yihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105614/
https://www.ncbi.nlm.nih.gov/pubmed/32266134
http://dx.doi.org/10.3389/fonc.2020.00334
_version_ 1783512432913678336
author Shi, Xiang
Zhou, Weiyan
Xu, Mengqiao
Hua, Tao
Guan, Yihui
author_facet Shi, Xiang
Zhou, Weiyan
Xu, Mengqiao
Hua, Tao
Guan, Yihui
author_sort Shi, Xiang
collection PubMed
description Precursor B-cell lymphoblastic lymphoma (PBLL) is a rare subtype of non-Hodgkin lymphoma originating from B-cell precursors. PBLL, as a solitary mass lesion affecting the central nervous system without leukemic disease at presentation, is quite uncommon. Here we report a rare PBLL case with Philadelphia chromosome positivity. The 44-year-old male presented a solitary bulky mass primarily involving the left frontotemporal lobes and extended into the infratemporal fossa. Pretreatment PET/CT imaging showed avid (18)F-fluorodeoxyglucose ((18)F-FDG) uptake of the lesion. By aggressive chemotherapy and imatinib maintenance treatment, the patient achieved and remained in complete remission on another two consecutive PET/CT imaging follow-ups.
format Online
Article
Text
id pubmed-7105614
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-71056142020-04-07 Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging Shi, Xiang Zhou, Weiyan Xu, Mengqiao Hua, Tao Guan, Yihui Front Oncol Oncology Precursor B-cell lymphoblastic lymphoma (PBLL) is a rare subtype of non-Hodgkin lymphoma originating from B-cell precursors. PBLL, as a solitary mass lesion affecting the central nervous system without leukemic disease at presentation, is quite uncommon. Here we report a rare PBLL case with Philadelphia chromosome positivity. The 44-year-old male presented a solitary bulky mass primarily involving the left frontotemporal lobes and extended into the infratemporal fossa. Pretreatment PET/CT imaging showed avid (18)F-fluorodeoxyglucose ((18)F-FDG) uptake of the lesion. By aggressive chemotherapy and imatinib maintenance treatment, the patient achieved and remained in complete remission on another two consecutive PET/CT imaging follow-ups. Frontiers Media S.A. 2020-03-24 /pmc/articles/PMC7105614/ /pubmed/32266134 http://dx.doi.org/10.3389/fonc.2020.00334 Text en Copyright © 2020 Shi, Zhou, Xu, Hua and Guan. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Shi, Xiang
Zhou, Weiyan
Xu, Mengqiao
Hua, Tao
Guan, Yihui
Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging
title Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging
title_full Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging
title_fullStr Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging
title_full_unstemmed Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging
title_short Successful Treatment for Adult Precursor B-Cell Lymphoblastic Lymphoma Involving Central Nervous System Monitored by (18)F-Fluorodeoxyglucose PET/CT Imaging
title_sort successful treatment for adult precursor b-cell lymphoblastic lymphoma involving central nervous system monitored by (18)f-fluorodeoxyglucose pet/ct imaging
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105614/
https://www.ncbi.nlm.nih.gov/pubmed/32266134
http://dx.doi.org/10.3389/fonc.2020.00334
work_keys_str_mv AT shixiang successfultreatmentforadultprecursorbcelllymphoblasticlymphomainvolvingcentralnervoussystemmonitoredby18ffluorodeoxyglucosepetctimaging
AT zhouweiyan successfultreatmentforadultprecursorbcelllymphoblasticlymphomainvolvingcentralnervoussystemmonitoredby18ffluorodeoxyglucosepetctimaging
AT xumengqiao successfultreatmentforadultprecursorbcelllymphoblasticlymphomainvolvingcentralnervoussystemmonitoredby18ffluorodeoxyglucosepetctimaging
AT huatao successfultreatmentforadultprecursorbcelllymphoblasticlymphomainvolvingcentralnervoussystemmonitoredby18ffluorodeoxyglucosepetctimaging
AT guanyihui successfultreatmentforadultprecursorbcelllymphoblasticlymphomainvolvingcentralnervoussystemmonitoredby18ffluorodeoxyglucosepetctimaging

Ejemplares similares