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Targeting ADAM10 in Cancer and Autoimmunity

Generating inhibitors for A Disintegrin And Metalloproteinase 10 (ADAM10), a zinc-dependent protease, was heavily invested in by the pharmaceutical industry starting over 20 years ago. There has been much enthusiasm in basic research for these inhibitors, with a multitude of studies generating signi...

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Detalles Bibliográficos
Autores principales: Smith, Timothy M., Tharakan, Anuj, Martin, Rebecca K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105615/
https://www.ncbi.nlm.nih.gov/pubmed/32265938
http://dx.doi.org/10.3389/fimmu.2020.00499