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Rapid Induction and Maintenance of Virus-Specific CD8(+) T(EMRA) and CD4(+) T(EM) Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans
Dengue virus (DENV) is a mosquito-borne flavivirus that causes serious human disease. The current lack of an effective vaccine to simultaneously protect against the four serotypes of DENV in seronegative individuals is a major unmet medical need. Further, the immunological basis for protective immun...
Autores principales: | Graham, Nancy, Eisenhauer, Phil, Diehl, Sean A., Pierce, Kristen K., Whitehead, Stephen S., Durbin, Anna P., Kirkpatrick, Beth D., Sette, Alessandro, Weiskopf, Daniela, Boyson, Jonathan E., Botten, Jason W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105617/ https://www.ncbi.nlm.nih.gov/pubmed/32265929 http://dx.doi.org/10.3389/fimmu.2020.00479 |
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