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Application of CT images in the diagnosis of lung cancer based on finite mixed model

Investigating the application of CT images when diagnosing lung cancer based on finite mixture model is the objective. Method: 120 clean healthy rats were taken as the research objects to establish lung cancer rat model and carry out lung CT image examination. After the successful CT image data prep...

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Autores principales: Li, Yuekao, Wang, Guangda, Li, Meng, Li, Jinpeng, Shi, Liang, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105698/
https://www.ncbi.nlm.nih.gov/pubmed/32256168
http://dx.doi.org/10.1016/j.sjbs.2020.02.022
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author Li, Yuekao
Wang, Guangda
Li, Meng
Li, Jinpeng
Shi, Liang
Li, Jian
author_facet Li, Yuekao
Wang, Guangda
Li, Meng
Li, Jinpeng
Shi, Liang
Li, Jian
author_sort Li, Yuekao
collection PubMed
description Investigating the application of CT images when diagnosing lung cancer based on finite mixture model is the objective. Method: 120 clean healthy rats were taken as the research objects to establish lung cancer rat model and carry out lung CT image examination. After the successful CT image data preprocessing, the image is segmented by different methods, which include lung nodule segmentation on the basis of Adaptive Particle Swarm Optimization – Gaussian mixture model (APSO-GMM), lung nodule segmentation on the basis of Adaptive Particle Swarm Optimization – gamma mixture model (APSO-GaMM), lung nodule segmentation based on statistical information and self-selected mixed distribution model, and lung nodule segmentation based on neighborhood information and self-selected mixed distribution model. The segmentation effect is evaluated. Results: Compared with the results of lung nodule segmentation based on statistical information and self-selected mixed distribution model, the Dice coefficient of lung nodule segmentation based on neighborhood information and self-selected mixed distribution model is higher, the relative final measurement accuracy is smaller, the segmentation is more accurate, but the running time is longer. Compared with APSO-GMM and APSO-GaMM, the dice value of self-selected mixed distribution model segmentation method is larger, and the final measurement accuracy is smaller. Conclusion: Among the five methods, the dice value of the self-selected mixed distribution model based on neighborhood information is the largest, and the relative accuracy of the final measurement is the smallest, indicating that the segmentation effect of the self-selected mixed distribution model based on neighborhood information is the best.
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spelling pubmed-71056982020-03-31 Application of CT images in the diagnosis of lung cancer based on finite mixed model Li, Yuekao Wang, Guangda Li, Meng Li, Jinpeng Shi, Liang Li, Jian Saudi J Biol Sci Article Investigating the application of CT images when diagnosing lung cancer based on finite mixture model is the objective. Method: 120 clean healthy rats were taken as the research objects to establish lung cancer rat model and carry out lung CT image examination. After the successful CT image data preprocessing, the image is segmented by different methods, which include lung nodule segmentation on the basis of Adaptive Particle Swarm Optimization – Gaussian mixture model (APSO-GMM), lung nodule segmentation on the basis of Adaptive Particle Swarm Optimization – gamma mixture model (APSO-GaMM), lung nodule segmentation based on statistical information and self-selected mixed distribution model, and lung nodule segmentation based on neighborhood information and self-selected mixed distribution model. The segmentation effect is evaluated. Results: Compared with the results of lung nodule segmentation based on statistical information and self-selected mixed distribution model, the Dice coefficient of lung nodule segmentation based on neighborhood information and self-selected mixed distribution model is higher, the relative final measurement accuracy is smaller, the segmentation is more accurate, but the running time is longer. Compared with APSO-GMM and APSO-GaMM, the dice value of self-selected mixed distribution model segmentation method is larger, and the final measurement accuracy is smaller. Conclusion: Among the five methods, the dice value of the self-selected mixed distribution model based on neighborhood information is the largest, and the relative accuracy of the final measurement is the smallest, indicating that the segmentation effect of the self-selected mixed distribution model based on neighborhood information is the best. Elsevier 2020-04 2020-03-04 /pmc/articles/PMC7105698/ /pubmed/32256168 http://dx.doi.org/10.1016/j.sjbs.2020.02.022 Text en © 2020 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Li, Yuekao
Wang, Guangda
Li, Meng
Li, Jinpeng
Shi, Liang
Li, Jian
Application of CT images in the diagnosis of lung cancer based on finite mixed model
title Application of CT images in the diagnosis of lung cancer based on finite mixed model
title_full Application of CT images in the diagnosis of lung cancer based on finite mixed model
title_fullStr Application of CT images in the diagnosis of lung cancer based on finite mixed model
title_full_unstemmed Application of CT images in the diagnosis of lung cancer based on finite mixed model
title_short Application of CT images in the diagnosis of lung cancer based on finite mixed model
title_sort application of ct images in the diagnosis of lung cancer based on finite mixed model
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105698/
https://www.ncbi.nlm.nih.gov/pubmed/32256168
http://dx.doi.org/10.1016/j.sjbs.2020.02.022
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