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Uremic Vascular Calcification Is Correlated With Oxidative Elastic Lamina Injury, Contractile Smooth Muscle Cell Loss, Osteogenesis, and Apoptosis: The Human Pathobiological Evidence

Background: Uremic vascular calcification (UVC) is reminiscent of osteogenesis and apoptosis in vascular smooth muscle cell (VSMC). We aimed to identify how circulating procalcific particles dramatically leak into VSMC layer in human tissue models of vascular rings. Methods: According to baseline es...

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Detalles Bibliográficos
Autores principales: Chang, Jia-Feng, Liu, Shih-Hao, Lu, Kuo-Cheng, Ka, Shuk-Man, Hsieh, Chih-Yu, Ho, Chun-Ta, Lin, Wei-Ning, Wen, Li-Li, Liou, Jian-Chiun, Chang, Shu-Wei, Wu, Chang-Chin, Wang, Ting-Ming, Li, Yen-Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105710/
https://www.ncbi.nlm.nih.gov/pubmed/32266272
http://dx.doi.org/10.3389/fmed.2020.00078