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Uremic Vascular Calcification Is Correlated With Oxidative Elastic Lamina Injury, Contractile Smooth Muscle Cell Loss, Osteogenesis, and Apoptosis: The Human Pathobiological Evidence
Background: Uremic vascular calcification (UVC) is reminiscent of osteogenesis and apoptosis in vascular smooth muscle cell (VSMC). We aimed to identify how circulating procalcific particles dramatically leak into VSMC layer in human tissue models of vascular rings. Methods: According to baseline es...
Autores principales: | Chang, Jia-Feng, Liu, Shih-Hao, Lu, Kuo-Cheng, Ka, Shuk-Man, Hsieh, Chih-Yu, Ho, Chun-Ta, Lin, Wei-Ning, Wen, Li-Li, Liou, Jian-Chiun, Chang, Shu-Wei, Wu, Chang-Chin, Wang, Ting-Ming, Li, Yen-Yao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105710/ https://www.ncbi.nlm.nih.gov/pubmed/32266272 http://dx.doi.org/10.3389/fmed.2020.00078 |
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