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Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort
OBJECTIVE: To describe the clinical features of early-onset androgenetic alopecia (AGA) in a large cohort of Chinese patients. METHODS: This descriptive study recruited consecutive patients seeking medical treatment for AGA between 1 January 2013 and 30 November 2018. Patients were included in the s...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105740/ https://www.ncbi.nlm.nih.gov/pubmed/32188323 http://dx.doi.org/10.1177/0300060519897190 |
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author | Ding, Qi Xu, Yu-Xuan Sun, Wei-Ling Liu, Jing-Jing Deng, Yu-Yu Wu, Qiao-Fang Cao, Chun-Yu Zhou, Lan-Bo Lu, Yan Fan, Wei-Xin |
author_facet | Ding, Qi Xu, Yu-Xuan Sun, Wei-Ling Liu, Jing-Jing Deng, Yu-Yu Wu, Qiao-Fang Cao, Chun-Yu Zhou, Lan-Bo Lu, Yan Fan, Wei-Xin |
author_sort | Ding, Qi |
collection | PubMed |
description | OBJECTIVE: To describe the clinical features of early-onset androgenetic alopecia (AGA) in a large cohort of Chinese patients. METHODS: This descriptive study recruited consecutive patients seeking medical treatment for AGA between 1 January 2013 and 30 November 2018. Patients were included in the study if they reported being ≤35 years old at AGA onset and if their pattern of hair loss was documented with photographs. The age of onset, sex, body mass index (BMI), BAsic and SPecific classification of hair loss and family history of alopecia were collected in an electronic database. RESULTS: A total of 3897 patients with early-onset AGA were recruited to the study. The majority of patients (70.6%; 2751 of 3897) were 21–30 years old and male (72.7%; 2834 of 3897). No association was found between high BMI (≥25 kg/m(2)) and early-onset AGA. There were significantly more overweight male AGA patients than overweight female patients (86.8% [632 of 728] versus 13.2% [96 of 728], respectively). The overall prevalence of familial AGA was 72.8% (2837 of 3897) and the condition was inherited more often from the father (52.8%; 1498 of 2837) than from the mother (24.3%; 688 of 2837). CONCLUSIONS: Early-onset AGA primarily affects male patients between 21–30 years of age. Males with early-onset AGA are likely to have inherited AGA from their fathers. |
format | Online Article Text |
id | pubmed-7105740 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-71057402020-04-03 Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort Ding, Qi Xu, Yu-Xuan Sun, Wei-Ling Liu, Jing-Jing Deng, Yu-Yu Wu, Qiao-Fang Cao, Chun-Yu Zhou, Lan-Bo Lu, Yan Fan, Wei-Xin J Int Med Res Retrospective Clinical Research Report OBJECTIVE: To describe the clinical features of early-onset androgenetic alopecia (AGA) in a large cohort of Chinese patients. METHODS: This descriptive study recruited consecutive patients seeking medical treatment for AGA between 1 January 2013 and 30 November 2018. Patients were included in the study if they reported being ≤35 years old at AGA onset and if their pattern of hair loss was documented with photographs. The age of onset, sex, body mass index (BMI), BAsic and SPecific classification of hair loss and family history of alopecia were collected in an electronic database. RESULTS: A total of 3897 patients with early-onset AGA were recruited to the study. The majority of patients (70.6%; 2751 of 3897) were 21–30 years old and male (72.7%; 2834 of 3897). No association was found between high BMI (≥25 kg/m(2)) and early-onset AGA. There were significantly more overweight male AGA patients than overweight female patients (86.8% [632 of 728] versus 13.2% [96 of 728], respectively). The overall prevalence of familial AGA was 72.8% (2837 of 3897) and the condition was inherited more often from the father (52.8%; 1498 of 2837) than from the mother (24.3%; 688 of 2837). CONCLUSIONS: Early-onset AGA primarily affects male patients between 21–30 years of age. Males with early-onset AGA are likely to have inherited AGA from their fathers. SAGE Publications 2020-03-18 /pmc/articles/PMC7105740/ /pubmed/32188323 http://dx.doi.org/10.1177/0300060519897190 Text en © The Author(s) 2020 https://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Retrospective Clinical Research Report Ding, Qi Xu, Yu-Xuan Sun, Wei-Ling Liu, Jing-Jing Deng, Yu-Yu Wu, Qiao-Fang Cao, Chun-Yu Zhou, Lan-Bo Lu, Yan Fan, Wei-Xin Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort |
title | Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort |
title_full | Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort |
title_fullStr | Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort |
title_full_unstemmed | Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort |
title_short | Early-onset androgenetic alopecia in China: a descriptive study of a large outpatient cohort |
title_sort | early-onset androgenetic alopecia in china: a descriptive study of a large outpatient cohort |
topic | Retrospective Clinical Research Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105740/ https://www.ncbi.nlm.nih.gov/pubmed/32188323 http://dx.doi.org/10.1177/0300060519897190 |
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