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Integration of virtual and physical screening
High-throughput screening (HTS) represents the dominant technique for the identification of new lead compounds in current drug discovery. It consists of physical screening (PS) of large libraries of chemicals against one or more specific biological targets. Virtual screening (VS) is a strategy for i...
Autores principales: | Fara, Dan C., Oprea, Tudor I., Prossnitz, Eric R., Bologa, Cristian G., Edwards, Bruce S., Sklar, Larry A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105924/ http://dx.doi.org/10.1016/j.ddtec.2006.11.003 |
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