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Child pneumonia – focus on the Western Pacific Region

Worldwide, pneumonia is the leading cause of death in infants and young children (aged <5 years). We provide an overview of the global pneumonia disease burden, as well as the aetiology and management practices in different parts of the world, with a specific focus on the WHO Western Pacific Regi...

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Autores principales: Nguyen, T.K.P., Tran, T.H., Roberts, C.L., Graham, S.M., Marais, B.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106312/
https://www.ncbi.nlm.nih.gov/pubmed/27569107
http://dx.doi.org/10.1016/j.prrv.2016.07.004
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author Nguyen, T.K.P.
Tran, T.H.
Roberts, C.L.
Graham, S.M.
Marais, B.J.
author_facet Nguyen, T.K.P.
Tran, T.H.
Roberts, C.L.
Graham, S.M.
Marais, B.J.
author_sort Nguyen, T.K.P.
collection PubMed
description Worldwide, pneumonia is the leading cause of death in infants and young children (aged <5 years). We provide an overview of the global pneumonia disease burden, as well as the aetiology and management practices in different parts of the world, with a specific focus on the WHO Western Pacific Region. In 2011, the Western Pacific region had an estimated 0.11 pneumonia episodes per child-year with 61,900 pneumonia-related deaths in children less than 5 years of age. The majority (>75%) of pneumonia deaths occurred in six countries; Cambodia, China, Laos, Papua New Guinea, the Philippines and Viet Nam. Historically Streptococcus pneumoniae and Haemophilus influenzae were the commonest causes of severe pneumonia and pneumonia-related deaths in young children, but this is changing with the introduction of highly effective conjugate vaccines and socio-economic development. The relative contribution of viruses and atypical bacteria appear to be increasing and traditional case management approaches may require revision to accommodate increased uptake of conjugated vaccines in the Western Pacific region. Careful consideration should be given to risk reduction strategies, enhanced vaccination coverage, improved management of hypoxaemia and antibiotic stewardship.
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spelling pubmed-71063122020-03-31 Child pneumonia – focus on the Western Pacific Region Nguyen, T.K.P. Tran, T.H. Roberts, C.L. Graham, S.M. Marais, B.J. Paediatr Respir Rev Article Worldwide, pneumonia is the leading cause of death in infants and young children (aged <5 years). We provide an overview of the global pneumonia disease burden, as well as the aetiology and management practices in different parts of the world, with a specific focus on the WHO Western Pacific Region. In 2011, the Western Pacific region had an estimated 0.11 pneumonia episodes per child-year with 61,900 pneumonia-related deaths in children less than 5 years of age. The majority (>75%) of pneumonia deaths occurred in six countries; Cambodia, China, Laos, Papua New Guinea, the Philippines and Viet Nam. Historically Streptococcus pneumoniae and Haemophilus influenzae were the commonest causes of severe pneumonia and pneumonia-related deaths in young children, but this is changing with the introduction of highly effective conjugate vaccines and socio-economic development. The relative contribution of viruses and atypical bacteria appear to be increasing and traditional case management approaches may require revision to accommodate increased uptake of conjugated vaccines in the Western Pacific region. Careful consideration should be given to risk reduction strategies, enhanced vaccination coverage, improved management of hypoxaemia and antibiotic stewardship. Elsevier Ltd. 2017-01 2016-07-18 /pmc/articles/PMC7106312/ /pubmed/27569107 http://dx.doi.org/10.1016/j.prrv.2016.07.004 Text en © 2016 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Nguyen, T.K.P.
Tran, T.H.
Roberts, C.L.
Graham, S.M.
Marais, B.J.
Child pneumonia – focus on the Western Pacific Region
title Child pneumonia – focus on the Western Pacific Region
title_full Child pneumonia – focus on the Western Pacific Region
title_fullStr Child pneumonia – focus on the Western Pacific Region
title_full_unstemmed Child pneumonia – focus on the Western Pacific Region
title_short Child pneumonia – focus on the Western Pacific Region
title_sort child pneumonia – focus on the western pacific region
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106312/
https://www.ncbi.nlm.nih.gov/pubmed/27569107
http://dx.doi.org/10.1016/j.prrv.2016.07.004
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