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Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promotes colorectal cancer progression

BACKGROUND: Tumor-associated macrophages (TAMs) in the tumor microenvironment influence tumor initiation, invasion and metastasis. Several studies have shown that Wnt5a is mainly expressed in the tumor stroma, especially in TAMs. However, whether Wnt5a regulates the polarization and biological funct...

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Detalles Bibliográficos
Autores principales: Liu, Qing, Yang, Chaogang, Wang, Shuyi, Shi, Dongdong, Wei, Chen, Song, Jialin, Lin, Xiaobin, Dou, Rongzhang, Bai, Jian, Xiang, Zhenxian, Huang, Sihao, Liu, Keshu, Xiong, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106599/
https://www.ncbi.nlm.nih.gov/pubmed/32228612
http://dx.doi.org/10.1186/s12964-020-00557-2

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