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Exogenous supply of Hsp47 triggers fibrillar collagen deposition in skin cell cultures in vitro
BACKGROUND: Collagen is a structural protein that provides mechanical stability and defined architectures to skin. In collagen-based skin disorders this stability is lost, either due to mutations in collagens or in the chaperones involved in collagen assembly. This leads to chronic wounds, skin frag...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106624/ https://www.ncbi.nlm.nih.gov/pubmed/32228452 http://dx.doi.org/10.1186/s12860-020-00267-0 |