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Immunization with virus-like particles conjugated to CIDRα1 domain of Plasmodium falciparum erythrocyte membrane protein 1 induces inhibitory antibodies

BACKGROUND: During the erythrocytic cycle, Plasmodium falciparum malaria parasites express P. falciparum Erythrocyte Membrane Protein 1 (PfEMP1) that anchor the infected erythrocytes (IE) to the vascular lining of the host. The CIDRα1 domain of PfEMP1 is responsible for binding host endothelial prot...

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Detalles Bibliográficos
Autores principales:	Harmsen, Charlotte, Turner, Louise, Thrane, Susan, Sander, Adam F., Theander, Thor G., Lavstsen, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106694/ https://www.ncbi.nlm.nih.gov/pubmed/32228596 http://dx.doi.org/10.1186/s12936-020-03201-z

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