Recent advances in radiotherapy of breast cancer

Radiation therapy is an integral part of the multidisciplinary management of breast cancer. Regional lymph node irradiation in younger trials seems to provide superior target coverage as well as a reduction in long-term toxicity resulting in a small benefit in the overall survival rate. For partial...

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Autores principales: Haussmann, Jan, Corradini, Stefanie, Nestle-Kraemling, Carolin, Bölke, Edwin, Njanang, Freddy Joel Djiepmo, Tamaskovics, Bálint, Orth, Klaus, Ruckhaeberle, Eugen, Fehm, Tanja, Mohrmann, Svjetlana, Simiantonakis, Ioannis, Budach, Wilfried, Matuschek, Christiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106718/
https://www.ncbi.nlm.nih.gov/pubmed/32228654
http://dx.doi.org/10.1186/s13014-020-01501-x
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author Haussmann, Jan
Corradini, Stefanie
Nestle-Kraemling, Carolin
Bölke, Edwin
Njanang, Freddy Joel Djiepmo
Tamaskovics, Bálint
Orth, Klaus
Ruckhaeberle, Eugen
Fehm, Tanja
Mohrmann, Svjetlana
Simiantonakis, Ioannis
Budach, Wilfried
Matuschek, Christiane
author_facet Haussmann, Jan
Corradini, Stefanie
Nestle-Kraemling, Carolin
Bölke, Edwin
Njanang, Freddy Joel Djiepmo
Tamaskovics, Bálint
Orth, Klaus
Ruckhaeberle, Eugen
Fehm, Tanja
Mohrmann, Svjetlana
Simiantonakis, Ioannis
Budach, Wilfried
Matuschek, Christiane
author_sort Haussmann, Jan
collection PubMed
description Radiation therapy is an integral part of the multidisciplinary management of breast cancer. Regional lymph node irradiation in younger trials seems to provide superior target coverage as well as a reduction in long-term toxicity resulting in a small benefit in the overall survival rate. For partial breast irradiation there are now two large trials available which support the role of partial breast irradiation in low risk breast cancer patients. Multiple randomized trials have established that a sequentially applied dose to the tumor bed improves local control with the cost of worse cosmetic results.
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spelling pubmed-71067182020-04-01 Recent advances in radiotherapy of breast cancer Haussmann, Jan Corradini, Stefanie Nestle-Kraemling, Carolin Bölke, Edwin Njanang, Freddy Joel Djiepmo Tamaskovics, Bálint Orth, Klaus Ruckhaeberle, Eugen Fehm, Tanja Mohrmann, Svjetlana Simiantonakis, Ioannis Budach, Wilfried Matuschek, Christiane Radiat Oncol Review Radiation therapy is an integral part of the multidisciplinary management of breast cancer. Regional lymph node irradiation in younger trials seems to provide superior target coverage as well as a reduction in long-term toxicity resulting in a small benefit in the overall survival rate. For partial breast irradiation there are now two large trials available which support the role of partial breast irradiation in low risk breast cancer patients. Multiple randomized trials have established that a sequentially applied dose to the tumor bed improves local control with the cost of worse cosmetic results. BioMed Central 2020-03-30 /pmc/articles/PMC7106718/ /pubmed/32228654 http://dx.doi.org/10.1186/s13014-020-01501-x Text en © The Author(s) 2020 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Haussmann, Jan
Corradini, Stefanie
Nestle-Kraemling, Carolin
Bölke, Edwin
Njanang, Freddy Joel Djiepmo
Tamaskovics, Bálint
Orth, Klaus
Ruckhaeberle, Eugen
Fehm, Tanja
Mohrmann, Svjetlana
Simiantonakis, Ioannis
Budach, Wilfried
Matuschek, Christiane
Recent advances in radiotherapy of breast cancer
title Recent advances in radiotherapy of breast cancer
title_full Recent advances in radiotherapy of breast cancer
title_fullStr Recent advances in radiotherapy of breast cancer
title_full_unstemmed Recent advances in radiotherapy of breast cancer
title_short Recent advances in radiotherapy of breast cancer
title_sort recent advances in radiotherapy of breast cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106718/
https://www.ncbi.nlm.nih.gov/pubmed/32228654
http://dx.doi.org/10.1186/s13014-020-01501-x
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