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The molecular characteristics of spinal cord gliomas with or without H3 K27M mutation
Due to the rare incidence of spinal cord astrocytomas, their molecular features remain unclear. Here, we characterized the landscapes of mutations in H3 K27M, isocitrate dehydrogenase 1 (IDH1) R132H, BRAF V600E, and the TERT promoter in 83 diffuse spinal cord astrocytic tumors. Among these samples,...
Autores principales: | Chai, Rui-Chao, Zhang, Yao-Wu, Liu, Yu-Qing, Chang, Yu-Zhou, Pang, Bo, Jiang, Tao, Jia, Wen-Qing, Wang, Yong-Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106747/ https://www.ncbi.nlm.nih.gov/pubmed/32228694 http://dx.doi.org/10.1186/s40478-020-00913-w |
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