Icariin Ameliorates Diabetic Cardiomyopathy Through Apelin/Sirt3 Signalling to Improve Mitochondrial Dysfunction

Myocardial contractile dysfunction in diabetic cardiomyocytes is a significant promoter of heart failure. Herein, we investigated the effect of icariin, a flavonoid monomer isolated from Epimedium, on diabetic cardiomyopathy (DCM) and explored the mechanisms underlying its unique pharmacological car...

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Detalles Bibliográficos
Autores principales: Ni, Tingjuan, Lin, Na, Huang, Xingxiao, Lu, Wenqiang, Sun, Zhenzhu, Zhang, Jie, Lin, Hui, Chi, Jufang, Guo, Hangyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106769/
https://www.ncbi.nlm.nih.gov/pubmed/32265695
http://dx.doi.org/10.3389/fphar.2020.00256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106769/
https://www.ncbi.nlm.nih.gov/pubmed/32265695
http://dx.doi.org/10.3389/fphar.2020.00256

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